Die equine coronavirus infektion ist eine virale infektionskrankheit beim pferd die durch das equine coronavirus ecov ausgelost wird 2 erreger das equine coronavirus ist ein behulltes spharisches rund 120 nm grosses rna virus aus der gattung betacoronavirus innerhalb der familie der coronaviridae. The equine influenza virus has evolved as an independent lineage to influenza viruses from other species we estimated the differences in antiviral activities between human mxa humxa and equine mx1 eqmx1 against a broad range of iav strains we found that humxa has antiviral potential against iav strains from non human species whereas eqmx1 could only inhibit the polymerase activity of non equine species here we demonstrated that np is the main target of eqmx1 subsequently we found . Common causes of viral respiratory tract infections in horses include equine influenza eiv equine herpes ehv 1 and 4 and equine rhinitis erav these viral infections are easily spread through fomite buckets manure forks stall walls and nose to nose contact young horses are especially prone due to additional stress from weaning training or changing locations and or pasture mates. Equine influenza rhinopneumonitis and equine viral arteritis are the three viral infections causing outbreaks of respiratory disease in north america african horse sickness although foreign to north america could be introduced despite stringent horse importation regulations specific antiviral therapy is not available to treat viral respiratory disease in the horse a variety of inactivated and modified live vaccines however are available to prevent clinical disease and the spread of